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Immunohistological Examination of AKT Isoforms in the Brain: Cell-Type Specificity That May Underlie AKT’s Role in Complex Brain Disorders and Neurological Disease

Protein kinase B (PKB/AKT) is a central kinase involved in many neurobiological processes. AKT is expressed in the brain as three isoforms, AKT1, AKT2, and AKT3. Previous studies suggest isoform-specific roles in neural function, but very few studies have examined AKT isoform expression at the cellu...

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Detalles Bibliográficos
Autores principales: Levenga, Josien, Wong, Helen, Milstead, Ryan, LaPlante, Lauren, Hoeffer, Charles A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8223503/
https://www.ncbi.nlm.nih.gov/pubmed/34296180
http://dx.doi.org/10.1093/texcom/tgab036