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OVX836 Heptameric Nucleoprotein Vaccine Generates Lung Tissue-Resident Memory CD8+ T-Cells for Cross-Protection Against Influenza

Tissue-resident memory (TRM) CD8+ T-cells play a crucial role in the protection against influenza infection but remain difficult to elicit using recombinant protein vaccines. OVX836 is a recombinant protein vaccine, obtained by the fusion of the DNA sequence of the influenza A nucleoprotein (NP) to...

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Detalles Bibliográficos
Autores principales: Del Campo, Judith, Bouley, Julien, Chevandier, Marion, Rousset, Carine, Haller, Marjorie, Indalecio, Alice, Guyon-Gellin, Delphine, Le Vert, Alexandre, Hill, Fergal, Djebali, Sophia, Leverrier, Yann, Marvel, Jacqueline, Combadière, Béhazine, Nicolas, Florence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8223747/
https://www.ncbi.nlm.nih.gov/pubmed/34177921
http://dx.doi.org/10.3389/fimmu.2021.678483