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Cross-Tissue Transcriptomic Analysis Leveraging Machine Learning Approaches Identifies New Biomarkers for Rheumatoid Arthritis

There is an urgent need to identify biomarkers for diagnosis and disease activity monitoring in rheumatoid arthritis (RA). We leveraged publicly available microarray gene expression data in the NCBI GEO database for whole blood (N=1,885) and synovial (N=284) tissues from RA patients and healthy cont...

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Detalles Bibliográficos
Autores principales: Rychkov, Dmitry, Neely, Jessica, Oskotsky, Tomiko, Yu, Steven, Perlmutter, Noah, Nititham, Joanne, Carvidi, Alexander, Krueger, Melissa, Gross, Andrew, Criswell, Lindsey A., Ashouri, Judith F., Sirota, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8223752/
https://www.ncbi.nlm.nih.gov/pubmed/34177888
http://dx.doi.org/10.3389/fimmu.2021.638066