Total Synthesis and Anti-Inflammatory Bioactivity of (−)-Majusculoic Acid and Its Derivatives

The first total synthesis of marine natural product, (−)-majusculoic acid (1) and its seven analogs (9–15), was accomplished in three to ten steps with a yield of 3% to 28%. The strategy featured the application of the conformational controlled establishment of the trans-cyclopropane and stereochemi...

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Detalles Bibliográficos
Autores principales: Xiao, Hong-Xiu, Yan, Qing-Xiang, He, Zhi-Hui, Zou, Zheng-Biao, Le, Qing-Qing, Chen, Ting-Ting, Cai, Bing, Yang, Xian-Wen, Luo, Su-Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8223986/
https://www.ncbi.nlm.nih.gov/pubmed/34063984
http://dx.doi.org/10.3390/md19060288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8223986/
https://www.ncbi.nlm.nih.gov/pubmed/34063984
http://dx.doi.org/10.3390/md19060288

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