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Solubility Enhancement of Ibuprofen by Adsorption onto Spherical Porous Calcium Silicate

The solubility of a drug is higher when it is in an amorphous form than when it is in a crystalline form. To enhance the solubility of ibuprofen (IBU), a poorly water-soluble drug, we attempted to adsorb IBU onto spherical porous calcium silicate (Florite(®) PS300, PS300) in two ways: the evaporatio...

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Detalles Bibliográficos
Autores principales: Kawano, Yayoi, Chen, Shiyang, Hanawa, Takehisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224037/
https://www.ncbi.nlm.nih.gov/pubmed/34063903
http://dx.doi.org/10.3390/pharmaceutics13060767