Novel Pharmacokinetic/Pharmacodynamic Parameters Quantify the Exposure–Effect Relationship of Levofloxacin against Fluoroquinolone-Resistant Escherichia coli

Minimal inhibitory concentration-based pharmacokinetic/pharmacodynamic (PK/PD) indices are commonly applied to antibiotic dosing optimisation, but their informative value is limited, as they do not account for bacterial growth dynamics over time. We aimed to comprehensively characterise the exposure...

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Detalles Bibliográficos
Autores principales: Seeger, Johanna, Guenther, Sebastian, Schaufler, Katharina, Heiden, Stefan E., Michelet, Robin, Kloft, Charlotte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224043/
https://www.ncbi.nlm.nih.gov/pubmed/34063980
http://dx.doi.org/10.3390/antibiotics10060615

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224043/
https://www.ncbi.nlm.nih.gov/pubmed/34063980
http://dx.doi.org/10.3390/antibiotics10060615

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