Onset of Senescence and Steatosis in Hepatocytes as a Consequence of a Shift in the Diacylglycerol/Ceramide Balance at the Plasma Membrane

Ceramide and diacylglycerol (DAG) are bioactive lipids and mediate many cellular signaling pathways. Sphingomyelin synthase (SMS) is the single metabolic link between the two, while SMS2 is the only SMS form located at the plasma membrane. SMS2 functions were investigated in HepG2 cell lines stably...

Descripción completa

Detalles Bibliográficos
Autores principales: Deevska, Gergana, Dotson, Patrick P., Mitov, Mihail, Butterfield, D. Allan, Nikolova-Karakashian, Mariana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224046/
https://www.ncbi.nlm.nih.gov/pubmed/34064003
http://dx.doi.org/10.3390/cells10061278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224046/
https://www.ncbi.nlm.nih.gov/pubmed/34064003
http://dx.doi.org/10.3390/cells10061278

Ejemplares similares