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Expression of Immuno-Oncologic Biomarkers Is Enriched in Colorectal Cancers and Other Solid Tumors Harboring the A59T Variant of KRAS

The molecular heterogeneity of KRAS is well established, with a pool of variants comprising >75% of all known mutations; this pool includes mutations in classic codons 12, 13, and 61, as well as 146 and 117. In addition, there are rare variants that are more frequently encountered clinically due...

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Detalles Bibliográficos
Autores principales: Lou, Emil, Xiu, Joanne, Baca, Yasmine, Nelson, Andrew C., Weinberg, Benjamin A., Beg, Muhammad Shaalan, Salem, Mohamed E., Lenz, Heinz-Josef, Philip, Philip, El-Deiry, Wafik S., Korn, W. Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224072/
https://www.ncbi.nlm.nih.gov/pubmed/34063999
http://dx.doi.org/10.3390/cells10061275