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Neuroprotective and anti-inflammatory effects of a therapy combining agonists of nicotinic α7 and σ1 receptors in a rat model of Parkinson’s disease

To date there is no treatment able to stop or slow down the loss of dopaminergic neurons that characterizes Parkinson’s disease. It was recently observed in a rodent model of Alzheimer’s disease that the interaction between the α7 subtype of nicotinic acetylcholine receptor (α7-nAChR) and sigma-1 re...

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Detalles Bibliográficos
Autores principales: Vetel, Steven, Foucault-Fruchard, Laura, Tronel, Claire, Buron, Frédéric, Vergote, Jackie, Bodard, Sylvie, Routier, Sylvain, Sérrière, Sophie, Chalon, Sylvie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224116/
https://www.ncbi.nlm.nih.gov/pubmed/33269756
http://dx.doi.org/10.4103/1673-5374.300451