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TP53-induced glycolysis and apoptosis regulator alleviates hypoxia/ischemia-induced microglial pyroptosis and ischemic brain damage

Our previous studies have demonstrated that TP53-induced glycolysis and apoptosis regulator (TIGAR) can protect neurons after cerebral ischemia/reperfusion. However, the role of TIGAR in neonatal hypoxic-ischemic brain damage (HIBD) remains unknown. In the present study, 7-day-old Sprague-Dawley rat...

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Detalles Bibliográficos
Autores principales: Tan, Lan-Lan, Jiang, Xiao-Lu, Xu, Li-Xiao, Li, Gen, Feng, Chen-Xi, Ding, Xin, Sun, Bin, Qin, Zheng-Hong, Zhang, Zu-Bin, Feng, Xing, Li, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224121/
https://www.ncbi.nlm.nih.gov/pubmed/33269748
http://dx.doi.org/10.4103/1673-5374.300453