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Proteomic Analysis of Rhesus Macaque Brain Explants Treated With Borrelia burgdorferi Identifies Host GAP-43 as a Potential Factor Associated With Lyme Neuroborreliosis

BACKGROUND: Lyme neuroborreliosis (LNB) is one of the most dangerous manifestations of Lyme disease, but the pathogenesis and inflammatory mechanisms are not fully understood. METHODS: Cultured explants from the frontal cortex of rhesus monkey brain (n=3) were treated with live Borrelia burgdorferi...

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Detalles Bibliográficos
Autores principales: Li, Lianbao, Luo, Lisha, Chen, Taigui, Cao, Wenjing, Xu, Xin, Zhang, Yu, Yue, Peng, Fan, Yuxin, Chen, Jingjing, Liu, Meixiao, Ma, Mingbiao, Tao, Lvyan, Peng, Yun, Dong, Yan, Li, Bingxue, Luo, Suyi, Kong, Jing, Zhou, Guozhong, Wen, Shiyuan, Liu, Aihua, Bao, Fukai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224226/
https://www.ncbi.nlm.nih.gov/pubmed/34178719
http://dx.doi.org/10.3389/fcimb.2021.647662