New insights into the catalytic mechanism of the SARS-CoV-2 main protease: an ONIOM QM/MM approach

ABSTRACT: SARS-CoV-2 M(pro), also known as the main protease or 3C-like protease, is a key enzyme involved in the replication process of the virus that is causing the COVID-19 pandemic. It is also the most promising antiviral drug target targeting SARS-CoV-2 virus. In this work, the catalytic mechan...

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Detalles Bibliográficos
Autores principales: Fernandes, Henrique S., Sousa, Sérgio F., Cerqueira, Nuno M. F. S. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224256/
https://www.ncbi.nlm.nih.gov/pubmed/34169450
http://dx.doi.org/10.1007/s11030-021-10259-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224256/
https://www.ncbi.nlm.nih.gov/pubmed/34169450
http://dx.doi.org/10.1007/s11030-021-10259-7

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