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New insights into the catalytic mechanism of the SARS-CoV-2 main protease: an ONIOM QM/MM approach
ABSTRACT: SARS-CoV-2 M(pro), also known as the main protease or 3C-like protease, is a key enzyme involved in the replication process of the virus that is causing the COVID-19 pandemic. It is also the most promising antiviral drug target targeting SARS-CoV-2 virus. In this work, the catalytic mechan...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224256/ https://www.ncbi.nlm.nih.gov/pubmed/34169450 http://dx.doi.org/10.1007/s11030-021-10259-7 |