Methylation of Estrogen Receptor 1 Gene in the Paraspinal Muscles of Girls with Idiopathic Scoliosis and Its Association with Disease Severity

Idiopathic scoliosis (IS) is a multifactorial disease with epigenetic modifications. Tissue dependent and differentially methylated regions (T-DMRs) may regulate tissue-specific expression of the estrogen receptor 1 gene (ESR1). This study aimed to analyze methylation levels within T-DMR1 and T-DMR2...

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Detalles Bibliográficos
Autores principales: Janusz, Piotr, Chmielewska, Małgorzata, Andrusiewicz, Mirosław, Kotwicka, Małgorzata, Kotwicki, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224318/
https://www.ncbi.nlm.nih.gov/pubmed/34064195
http://dx.doi.org/10.3390/genes12060790

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224318/
https://www.ncbi.nlm.nih.gov/pubmed/34064195
http://dx.doi.org/10.3390/genes12060790

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