Glucose-Impaired Corneal Re-Epithelialization Is Promoted by a Novel Derivate of Dimethyl Fumarate

Glucose induces corneal epithelial dysfunctions characterized by delayed wound repair. Nuclear erythroid 2-related factor 2 (Nrf2) mediates cell protection mechanisms even through the Heme oxygenase-1 (HO-1) up-regulation. Here, we synthesized new HO-1 inducers by modifying dimethyl fumarate (DMF) a...

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Detalles Bibliográficos
Autores principales: Giurdanella, Giovanni, Longo, Anna, Salerno, Loredana, Romeo, Giuseppe, Intagliata, Sebastiano, Lupo, Gabriella, Distefano, Alfio, Platania, Chiara Bianca Maria, Bucolo, Claudio, Li Volti, Giovanni, Anfuso, Carmelina Daniela, Pittalà, Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224583/
https://www.ncbi.nlm.nih.gov/pubmed/34067436
http://dx.doi.org/10.3390/antiox10060831

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224583/
https://www.ncbi.nlm.nih.gov/pubmed/34067436
http://dx.doi.org/10.3390/antiox10060831

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