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Glucose-Impaired Corneal Re-Epithelialization Is Promoted by a Novel Derivate of Dimethyl Fumarate
Glucose induces corneal epithelial dysfunctions characterized by delayed wound repair. Nuclear erythroid 2-related factor 2 (Nrf2) mediates cell protection mechanisms even through the Heme oxygenase-1 (HO-1) up-regulation. Here, we synthesized new HO-1 inducers by modifying dimethyl fumarate (DMF) a...
Autores principales: | Giurdanella, Giovanni, Longo, Anna, Salerno, Loredana, Romeo, Giuseppe, Intagliata, Sebastiano, Lupo, Gabriella, Distefano, Alfio, Platania, Chiara Bianca Maria, Bucolo, Claudio, Li Volti, Giovanni, Anfuso, Carmelina Daniela, Pittalà, Valeria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224583/ https://www.ncbi.nlm.nih.gov/pubmed/34067436 http://dx.doi.org/10.3390/antiox10060831 |
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