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DEER Analysis of GPCR Conformational Heterogeneity
G protein-coupled receptors (GPCRs) represent a large class of transmembrane helical proteins which are involved in numerous physiological signaling pathways and therefore represent crucial pharmacological targets. GPCR function and the action of therapeutic molecules are defined by only a few param...
Autores principales: | Elgeti, Matthias, Hubbell, Wayne L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224605/ https://www.ncbi.nlm.nih.gov/pubmed/34067265 http://dx.doi.org/10.3390/biom11060778 |
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