DEER Analysis of GPCR Conformational Heterogeneity

G protein-coupled receptors (GPCRs) represent a large class of transmembrane helical proteins which are involved in numerous physiological signaling pathways and therefore represent crucial pharmacological targets. GPCR function and the action of therapeutic molecules are defined by only a few param...

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Detalles Bibliográficos
Autores principales: Elgeti, Matthias, Hubbell, Wayne L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224605/
https://www.ncbi.nlm.nih.gov/pubmed/34067265
http://dx.doi.org/10.3390/biom11060778