Diagnosis of Sickle Cell Disease and HBB Haplotyping in the Era of Personalized Medicine: Role of Next Generation Sequencing

Hemoglobin genotype and HBB haplotype are established genetic factors that modify the clinical phenotype in sickle cell disease (SCD). Current methods of establishing these two factors are cumbersome and/or prone to errors. The throughput capability of next generation sequencing (NGS) makes it ideal...

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Detalles Bibliográficos
Autores principales: Adekile, Adekunle, Akbulut-Jeradi, Nagihan, Al Khaldi, Rasha, Fernandez, Maria Jinky, Sukumaran, Jalaja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224627/
https://www.ncbi.nlm.nih.gov/pubmed/34071035
http://dx.doi.org/10.3390/jpm11060454

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224627/
https://www.ncbi.nlm.nih.gov/pubmed/34071035
http://dx.doi.org/10.3390/jpm11060454

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