Lipophilicity, Pharmacokinetic Properties, and Molecular Docking Study on SARS-CoV-2 Target for Betulin Triazole Derivatives with Attached 1,4-Quinone

A key parameter in the design of new active compounds is lipophilicity, which influences the solubility and permeability through membranes. Lipophilicity affects the pharmacodynamic and toxicological profiles of compounds. These parameters can be determined experimentally or by using different calcu...

Descripción completa

Detalles Bibliográficos
Autores principales: Kadela-Tomanek, Monika, Jastrzębska, Maria, Marciniec, Krzysztof, Chrobak, Elwira, Bębenek, Ewa, Boryczka, Stanisław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224687/
https://www.ncbi.nlm.nih.gov/pubmed/34071116
http://dx.doi.org/10.3390/pharmaceutics13060781

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224687/
https://www.ncbi.nlm.nih.gov/pubmed/34071116
http://dx.doi.org/10.3390/pharmaceutics13060781

Ejemplares similares