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Lipophilicity, Pharmacokinetic Properties, and Molecular Docking Study on SARS-CoV-2 Target for Betulin Triazole Derivatives with Attached 1,4-Quinone
A key parameter in the design of new active compounds is lipophilicity, which influences the solubility and permeability through membranes. Lipophilicity affects the pharmacodynamic and toxicological profiles of compounds. These parameters can be determined experimentally or by using different calcu...
Autores principales: | Kadela-Tomanek, Monika, Jastrzębska, Maria, Marciniec, Krzysztof, Chrobak, Elwira, Bębenek, Ewa, Boryczka, Stanisław |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224687/ https://www.ncbi.nlm.nih.gov/pubmed/34071116 http://dx.doi.org/10.3390/pharmaceutics13060781 |
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