Mechanisms That Activate 26S Proteasomes and Enhance Protein Degradation

Although ubiquitination is widely assumed to be the only regulated step in the ubiquitin–proteasome pathway, recent studies have demonstrated several important mechanisms that regulate the activities of the 26S proteasome. Most proteasomes in cells are inactive but, upon binding a ubiquitinated subs...

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Detalles Bibliográficos
Autores principales: Goldberg, Alfred L., Kim, Hyoung Tae, Lee, Donghoon, Collins, Galen Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224753/
https://www.ncbi.nlm.nih.gov/pubmed/34067263
http://dx.doi.org/10.3390/biom11060779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224753/
https://www.ncbi.nlm.nih.gov/pubmed/34067263
http://dx.doi.org/10.3390/biom11060779

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