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Immunoglobulin gene rearrangement in Koreans with multiple myeloma: Clonality assessment and repertoire analysis using next-generation sequencing

INTRODUCTION: We assessed the applicability of next-generation sequencing (NGS)-based IGH/IGK clonality testing and analyzed the repertoire of immunoglobulin heavy chain (IGH) or immunoglobulin kappa light chain (IGK) gene usage in Korean patients with multiple myeloma (MM) for the first time. METHO...

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Detalles Bibliográficos
Autores principales: Kim, Miyoung, Jeon, Kibum, Hutt, Kasey, Zlotnicki, Alyssa M., Kim, Hyo Jung, Lee, Jiwon, Kim, Han-Sung, Kang, Hee Jung, Lee, Young Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224885/
https://www.ncbi.nlm.nih.gov/pubmed/34166440
http://dx.doi.org/10.1371/journal.pone.0253541