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Free energy landscape of RNA binding dynamics in start codon recognition by eukaryotic ribosomal pre-initiation complex

Specific interaction between the start codon, 5’-AUG-3’, and the anticodon, 5’-CAU-3’, ensures accurate initiation of translation. Recent studies show that several near-cognate start codons (e.g. GUG and CUG) can play a role in initiating translation in eukaryotes. However, the mechanism allowing in...

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Detalles Bibliográficos
Autores principales: Kameda, Takeru, Asano, Katsura, Togashi, Yuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224888/
https://www.ncbi.nlm.nih.gov/pubmed/34125830
http://dx.doi.org/10.1371/journal.pcbi.1009068