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Genome-wide binding analysis of 195 DNA binding proteins reveals “reservoir” promoters and human specific SVA-repeat family regulation

A key aspect in defining cell state is the complex choreography of DNA binding events in a given cell type, which in turn establishes a cell-specific gene-expression program. Here we wanted to take a deep analysis of DNA binding events and transcriptional output of a single cell state (K562 cells)....

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Detalles Bibliográficos
Autores principales: Smallegan, Michael J., Shehata, Soraya, Spradlin, Savannah F., Swearingen, Alison, Wheeler, Graycen, Das, Arpan, Corbet, Giulia, Nebenfuehr, Benjamin, Ahrens, Daniel, Tauber, Devin, Lennon, Shelby, Choi, Kevin, Huynh, Thao, Wieser, Tom, Schneider, Kristen, Bradshaw, Michael, Basken, Joel, Lai, Maria, Read, Timothy, Hynes-Grace, Matt, Timmons, Dan, Demasi, Jon, Rinn, John L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224974/
https://www.ncbi.nlm.nih.gov/pubmed/34166368
http://dx.doi.org/10.1371/journal.pone.0237055