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Genome-wide binding analysis of 195 DNA binding proteins reveals “reservoir” promoters and human specific SVA-repeat family regulation
A key aspect in defining cell state is the complex choreography of DNA binding events in a given cell type, which in turn establishes a cell-specific gene-expression program. Here we wanted to take a deep analysis of DNA binding events and transcriptional output of a single cell state (K562 cells)....
Autores principales: | Smallegan, Michael J., Shehata, Soraya, Spradlin, Savannah F., Swearingen, Alison, Wheeler, Graycen, Das, Arpan, Corbet, Giulia, Nebenfuehr, Benjamin, Ahrens, Daniel, Tauber, Devin, Lennon, Shelby, Choi, Kevin, Huynh, Thao, Wieser, Tom, Schneider, Kristen, Bradshaw, Michael, Basken, Joel, Lai, Maria, Read, Timothy, Hynes-Grace, Matt, Timmons, Dan, Demasi, Jon, Rinn, John L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224974/ https://www.ncbi.nlm.nih.gov/pubmed/34166368 http://dx.doi.org/10.1371/journal.pone.0237055 |
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