Correct dosage of X chromosome transcription is controlled by a nuclear pore component

Dosage compensation in Drosophila melanogaster involves a 2-fold transcriptional upregulation of the male X chromosome, which relies on the X-chromosome-binding males-specific lethal (MSL) complex. However, how such 2-fold precision is accomplished remains unclear. Here, we show that a nuclear pore...

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Detalles Bibliográficos
Autores principales: Aleman, Jennifer R., Kuhn, Terra M., Pascual-Garcia, Pau, Gospocic, Janko, Lan, Yemin, Bonasio, Roberto, Little, Shawn C., Capelson, Maya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224986/
https://www.ncbi.nlm.nih.gov/pubmed/34133927
http://dx.doi.org/10.1016/j.celrep.2021.109236

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224986/
https://www.ncbi.nlm.nih.gov/pubmed/34133927
http://dx.doi.org/10.1016/j.celrep.2021.109236

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