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Correct dosage of X chromosome transcription is controlled by a nuclear pore component
Dosage compensation in Drosophila melanogaster involves a 2-fold transcriptional upregulation of the male X chromosome, which relies on the X-chromosome-binding males-specific lethal (MSL) complex. However, how such 2-fold precision is accomplished remains unclear. Here, we show that a nuclear pore...
Autores principales: | Aleman, Jennifer R., Kuhn, Terra M., Pascual-Garcia, Pau, Gospocic, Janko, Lan, Yemin, Bonasio, Roberto, Little, Shawn C., Capelson, Maya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224986/ https://www.ncbi.nlm.nih.gov/pubmed/34133927 http://dx.doi.org/10.1016/j.celrep.2021.109236 |
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