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Hepatic Nfe2l2 Is Not an Essential Mediator of the Metabolic Phenotype Produced by Dietary Methionine Restriction

The principal sensing of dietary methionine restriction (MR) occurs in the liver, where it activates multiple transcriptional programs that mediate various biological components of the response. Hepatic Fgf21 is a key target and essential endocrine mediator of the metabolic phenotype produced by die...

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Detalles Bibliográficos
Autores principales: Fang, Han, Stone, Kirsten P., Ghosh, Sujoy, Forney, Laura A., Sims, Landon C., Vincik, LeighAnn, Gettys, Thomas W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225036/
https://www.ncbi.nlm.nih.gov/pubmed/34073838
http://dx.doi.org/10.3390/nu13061788