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Chemical Synthesis and Structure-Activity Relationship Study Yield Desotamide a Analogues with Improved Antibacterial Activity

Desotamides A, a cyclohexapeptide produced by the deep-sea-derived Streptomyces scopuliridis SCSIO ZJ46, displays notable antibacterial activities against strains of Streptococcus pnuemoniae, Staphylococcus aureus, and methicillin-resistant Staphylococcus epidermidis (MRSE). In this study, to furthe...

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Detalles Bibliográficos
Autores principales: Xu, Run, Song, Yongxiang, Li, Jun, Ju, Jianhua, Li, Qinglian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225045/
https://www.ncbi.nlm.nih.gov/pubmed/34073984
http://dx.doi.org/10.3390/md19060303