Cargando…

Epipregnanolone as a Positive Modulator of GABA(A) Receptor in Rat Cerebellar and Hippocampus Neurons

Epipregnanolone (3β-hydroxy-5β-pregnan-20-one, Epi) is an endogenous steroid with important physiological effects and high affinity for GABA(A) receptors. The effect of Epi on GABA-induced chloride current (I(GABA)) in native neurons has hardly been studied. In this work, we studied the influence of...

Descripción completa

Detalles Bibliográficos
Autores principales: Bukanova, Julia, Solntseva, Elena, Kondratenko, Rodion, Kudova, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225200/
https://www.ncbi.nlm.nih.gov/pubmed/34074021
http://dx.doi.org/10.3390/biom11060791