The Orai1-AC8 Interplay: How Breast Cancer Cells Escape from Orai1 Channel Inactivation

The interplay between the Ca(2+)-sensitive adenylyl cyclase 8 (AC8) and Orai1 channels plays an important role both in the activation of the cAMP/PKA signaling and the modulation of Orai1-dependent Ca(2+) signals. AC8 interacts with a N-terminal region that is exclusive to the Orai1 long variant, Or...

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Detalles Bibliográficos
Autores principales: Sánchez-Collado, José, López, José J., Rosado, Juan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225208/
https://www.ncbi.nlm.nih.gov/pubmed/34070268
http://dx.doi.org/10.3390/cells10061308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225208/
https://www.ncbi.nlm.nih.gov/pubmed/34070268
http://dx.doi.org/10.3390/cells10061308

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