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The Orai1-AC8 Interplay: How Breast Cancer Cells Escape from Orai1 Channel Inactivation
The interplay between the Ca(2+)-sensitive adenylyl cyclase 8 (AC8) and Orai1 channels plays an important role both in the activation of the cAMP/PKA signaling and the modulation of Orai1-dependent Ca(2+) signals. AC8 interacts with a N-terminal region that is exclusive to the Orai1 long variant, Or...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225208/ https://www.ncbi.nlm.nih.gov/pubmed/34070268 http://dx.doi.org/10.3390/cells10061308 |