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ELAVL1 primarily couples mRNA stability with the 3′ UTRs of interferon-stimulated genes

Upon pathogen detection, the innate immune system triggers signaling events leading to upregulation of pro-inflammatory and anti-microbial mRNA transcripts. RNA-binding proteins (RBPs) interact with these critical mRNAs and regulate their fates at the post-transcriptional level. One such RBP is ELAV...

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Detalles Bibliográficos
Autores principales: Rothamel, Katherine, Arcos, Sarah, Kim, Byungil, Reasoner, Clara, Lisy, Samantha, Mukherjee, Neelanjan, Ascano, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225249/
https://www.ncbi.nlm.nih.gov/pubmed/34038724
http://dx.doi.org/10.1016/j.celrep.2021.109178