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ELAVL1 primarily couples mRNA stability with the 3′ UTRs of interferon-stimulated genes
Upon pathogen detection, the innate immune system triggers signaling events leading to upregulation of pro-inflammatory and anti-microbial mRNA transcripts. RNA-binding proteins (RBPs) interact with these critical mRNAs and regulate their fates at the post-transcriptional level. One such RBP is ELAV...
Autores principales: | Rothamel, Katherine, Arcos, Sarah, Kim, Byungil, Reasoner, Clara, Lisy, Samantha, Mukherjee, Neelanjan, Ascano, Manuel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225249/ https://www.ncbi.nlm.nih.gov/pubmed/34038724 http://dx.doi.org/10.1016/j.celrep.2021.109178 |
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