T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1

The nuclear pore complex (NPC) is the sole and selective gateway for nuclear transport, and its dysfunction has been associated with many diseases. The metazoan NPC subcomplex RanBP2, which consists of RanBP2 (Nup358), RanGAP1-SUMO1, and Ubc9, regulates the assembly and function of the NPC. The role...

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Detalles Bibliográficos
Autores principales: He, Yujiao, Yang, Zhiguo, Zhao, Chen-si, Xiao, Zhihui, Gong, Yu, Li, Yun-Yi, Chen, Yiqi, Du, Yunting, Feng, Dianying, Altman, Amnon, Li, Yingqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225385/
https://www.ncbi.nlm.nih.gov/pubmed/34110283
http://dx.doi.org/10.7554/eLife.67123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225385/
https://www.ncbi.nlm.nih.gov/pubmed/34110283
http://dx.doi.org/10.7554/eLife.67123

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