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Pharmic Activation of PKG2 Alleviates Diabetes-Induced Osteoblast Dysfunction by Suppressing PLCβ1-Ca(2+)-Mediated Endoplasmic Reticulum Stress

As reported in our previous study, cinaciguat can improve implant osseointegration in type 2 diabetes mellitus (T2DM) rats by reactivating type 2 cGMP-dependent protein kinase (PKG2), but the downstream mechanisms remain unclear. In the present study, we investigated the favorable effect of cinacigu...

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Detalles Bibliográficos
Autores principales:	Jia, Tingting, Wang, Ya-nan, Feng, Yao, Wang, Chenchen, Zhang, Dongjiao, Xu, Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225424/ https://www.ncbi.nlm.nih.gov/pubmed/34221234 http://dx.doi.org/10.1155/2021/5552530

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