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Ethnic Identity and Genome Wide Runs of Homozygosity

It is long known that inbreeding increases the detrimental effects of recessive sequence variants in “Runs of Homozygosity” (ROHs). However, although the phenotypic association of ROH has been investigated for a variety of traits, the statistical power of the results often remains limited as a suffi...

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Detalles Bibliográficos
Autores principales: Fieder, Martin, Mitchell, Brittany L., Gordon, Scott, Huber, Susanne, Martin, Nicholas G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225526/
https://www.ncbi.nlm.nih.gov/pubmed/33723681
http://dx.doi.org/10.1007/s10519-021-10053-z