The c-Abl inhibitor, radotinib induces apoptosis in multiple myeloma cells via mitochondrial-dependent pathway

Multiple myeloma (MM) is a hematological cancer resulting from accumulated abnormal plasma cells. Unfortunately, MM remains an incurable disease, as relapse is very common. Therefore, there is urgent need to develop new treatment options for MM. Radotinib is a novel anti-cancer drug, currently appro...

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Detalles Bibliográficos
Autores principales: Heo, Sook-Kyoung, Noh, Eui-Kyu, Kim, Jeong Yi, Yu, Ho-Min, Sung, Jun Young, Ju, Lan Jeong, Kim, Do Kyoung, Seo, Hye Jin, Lee, Yoo Jin, Cheon, Jaekyung, Koh, SuJin, Min, Young Joo, Choi, Yunsuk, Jo, Jae-Cheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225673/
https://www.ncbi.nlm.nih.gov/pubmed/34168229
http://dx.doi.org/10.1038/s41598-021-92651-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225673/
https://www.ncbi.nlm.nih.gov/pubmed/34168229
http://dx.doi.org/10.1038/s41598-021-92651-9

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