High Th2 cytokine levels and upper airway inflammation in human inherited T-bet deficiency

We have described a child suffering from Mendelian susceptibility to mycobacterial disease (MSMD) due to autosomal recessive, complete T-bet deficiency, which impairs IFN-γ production by innate and innate-like adaptive, but not mycobacterial-reactive purely adaptive, lymphocytes. Here, we explore th...

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Detalles Bibliográficos
Autores principales: Yang, Rui, Weisshaar, Marc, Mele, Federico, Benhsaien, Ibtihal, Dorgham, Karim, Han, Jing, Croft, Carys A., Notarbartolo, Samuele, Rosain, Jérémie, Bastard, Paul, Puel, Anne, Fleckenstein, Bernhard, Glimcher, Laurie H., Di Santo, James P., Ma, Cindy S., Gorochov, Guy, Bousfiha, Aziz, Abel, Laurent, Tangye, Stuart G., Casanova, Jean-Laurent, Bustamante, Jacinta, Sallusto, Federica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225679/
https://www.ncbi.nlm.nih.gov/pubmed/34160550
http://dx.doi.org/10.1084/jem.20202726

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225679/
https://www.ncbi.nlm.nih.gov/pubmed/34160550
http://dx.doi.org/10.1084/jem.20202726

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