Guided extraction of genome-scale metabolic models for the integration and analysis of omics data

Omics data can be integrated into a reference model using various model extraction methods (MEMs) to yield context-specific genome-scale metabolic models (GEMs). How to chose the appropriate MEM, thresholding rule and threshold remains a challenge. We integrated mouse transcriptomic data from a Cyp5...

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Detalles Bibliográficos
Autores principales: Walakira, Andrew, Rozman, Damjana, Režen, Tadeja, Mraz, Miha, Moškon, Miha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Method Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225705/
https://www.ncbi.nlm.nih.gov/pubmed/34194675
http://dx.doi.org/10.1016/j.csbj.2021.06.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225705/
https://www.ncbi.nlm.nih.gov/pubmed/34194675
http://dx.doi.org/10.1016/j.csbj.2021.06.009

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