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Guided extraction of genome-scale metabolic models for the integration and analysis of omics data
Omics data can be integrated into a reference model using various model extraction methods (MEMs) to yield context-specific genome-scale metabolic models (GEMs). How to chose the appropriate MEM, thresholding rule and threshold remains a challenge. We integrated mouse transcriptomic data from a Cyp5...
Autores principales: | Walakira, Andrew, Rozman, Damjana, Režen, Tadeja, Mraz, Miha, Moškon, Miha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225705/ https://www.ncbi.nlm.nih.gov/pubmed/34194675 http://dx.doi.org/10.1016/j.csbj.2021.06.009 |
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