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Antiviral effect of high-dose ivermectin in adults with COVID-19: A proof-of-concept randomized trial

BACKGROUND: There are limited antiviral options for the treatment of patients with COVID-19. Ivermectin (IVM), a macrocyclic lactone with a wide anti-parasitary spectrum, has shown potent activity against SARS-CoV-2 in vitro. This study aimed at assessing the antiviral effect of IVM on viral load of...

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Detalles Bibliográficos
Autores principales: Krolewiecki, Alejandro, Lifschitz, Adrián, Moragas, Matías, Travacio, Marina, Valentini, Ricardo, Alonso, Daniel F., Solari, Rubén, Tinelli, Marcelo A., Cimino, Rubén O., Álvarez, Luis, Fleitas, Pedro E., Ceballos, Laura, Golemba, Marcelo, Fernández, Florencia, Fernández de Oliveira, Diego, Astudillo, German, Baeck, Inés, Farina, Javier, Cardama, Georgina A., Mangano, Andrea, Spitzer, Eduardo, Gold, Silvia, Lanusse, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225706/
https://www.ncbi.nlm.nih.gov/pubmed/34189446
http://dx.doi.org/10.1016/j.eclinm.2021.100959