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Nuclear factor E2-related factor 2 (NRF2) deficiency accelerates fast fibre type transition in soleus muscle during space flight

Microgravity induces skeletal muscle atrophy, particularly in the soleus muscle, which is predominantly composed of slow-twitch myofibre (type I) and is sensitive to disuse. Muscle atrophy is commonly known to be associated with increased production of reactive oxygen species. However, the role of N...

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Detalles Bibliográficos
Autores principales: Hayashi, Takuto, Kudo, Takashi, Fujita, Ryo, Fujita, Shin-ichiro, Tsubouchi, Hirona, Fuseya, Sayaka, Suzuki, Riku, Hamada, Michito, Okada, Risa, Muratani, Masafumi, Shiba, Dai, Suzuki, Takafumi, Warabi, Eiji, Yamamoto, Masayuki, Takahashi, Satoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225765/
https://www.ncbi.nlm.nih.gov/pubmed/34168270
http://dx.doi.org/10.1038/s42003-021-02334-4