Desmoglein-2 harnesses a PDZ-GEF2/Rap1 signaling axis to control cell spreading and focal adhesions independent of cell–cell adhesion

Desmosomes have a central role in mediating extracellular adhesion between cells, but they also coordinate other biological processes such as proliferation, differentiation, apoptosis and migration. In particular, several lines of evidence have implicated desmosomal proteins in regulating the actin...

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Detalles Bibliográficos
Autores principales: Shelton, W. Tucker, Thomas, S. Madison, Alexander, Hunter R., Thomes, C. Evan, Conway, Daniel E., Dubash, Adi D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225821/
https://www.ncbi.nlm.nih.gov/pubmed/34168237
http://dx.doi.org/10.1038/s41598-021-92675-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225821/
https://www.ncbi.nlm.nih.gov/pubmed/34168237
http://dx.doi.org/10.1038/s41598-021-92675-1

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