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Indispensable epigenetic control of thymic epithelial cell development and function by polycomb repressive complex 2

Thymic T cell development and T cell receptor repertoire selection are dependent on essential molecular cues provided by thymic epithelial cells (TEC). TEC development and function are regulated by their epigenetic landscape, in which the repressive H3K27me3 epigenetic marks are catalyzed by polycom...

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Detalles Bibliográficos
Autores principales: Barthlott, Thomas, Handel, Adam E., Teh, Hong Ying, Wirasinha, Rushika C., Hafen, Katrin, Žuklys, Saulius, Roch, Benoit, Orkin, Stuart H., de Villartay, Jean-Pierre, Daley, Stephen R., Holländer, Georg A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225857/
https://www.ncbi.nlm.nih.gov/pubmed/34168132
http://dx.doi.org/10.1038/s41467-021-24158-w