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TGF-β-dependent reprogramming of amino acid metabolism induces epithelial–mesenchymal transition in non-small cell lung cancers

Epithelial–mesenchymal transition (EMT)—a fundamental process in embryogenesis and wound healing—promotes tumor metastasis and resistance to chemotherapy. While studies have identified signaling components and transcriptional factors responsible in the TGF-β-dependent EMT, whether and how intracellu...

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Detalles Bibliográficos
Autores principales: Nakasuka, Fumie, Tabata, Sho, Sakamoto, Takeharu, Hirayama, Akiyoshi, Ebi, Hiromichi, Yamada, Tadaaki, Umetsu, Ko, Ohishi, Maki, Ueno, Ayano, Goto, Hisatsugu, Sugimoto, Masahiro, Nishioka, Yasuhiko, Yamada, Yasuhiro, Tomita, Masaru, Sasaki, Atsuo T., Yano, Seiji, Soga, Tomoyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225889/
https://www.ncbi.nlm.nih.gov/pubmed/34168290
http://dx.doi.org/10.1038/s42003-021-02323-7