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TGF-β-dependent reprogramming of amino acid metabolism induces epithelial–mesenchymal transition in non-small cell lung cancers
Epithelial–mesenchymal transition (EMT)—a fundamental process in embryogenesis and wound healing—promotes tumor metastasis and resistance to chemotherapy. While studies have identified signaling components and transcriptional factors responsible in the TGF-β-dependent EMT, whether and how intracellu...
Autores principales: | Nakasuka, Fumie, Tabata, Sho, Sakamoto, Takeharu, Hirayama, Akiyoshi, Ebi, Hiromichi, Yamada, Tadaaki, Umetsu, Ko, Ohishi, Maki, Ueno, Ayano, Goto, Hisatsugu, Sugimoto, Masahiro, Nishioka, Yasuhiko, Yamada, Yasuhiro, Tomita, Masaru, Sasaki, Atsuo T., Yano, Seiji, Soga, Tomoyoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225889/ https://www.ncbi.nlm.nih.gov/pubmed/34168290 http://dx.doi.org/10.1038/s42003-021-02323-7 |
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