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SARS-CoV-2 Spike Protein Induces Degradation of Junctional Proteins That Maintain Endothelial Barrier Integrity

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) uses the Angiotensin converting enzyme 2 (ACE2) receptor present on the cell surface to enter cells. Angiotensin converting enzyme 2 is present in many cell types including endothelial cells, where it functions to protect against oxidative...

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Detalles Bibliográficos
Autores principales: Raghavan, Somasundaram, Kenchappa, Divya Borsandra, Leo, M. Dennis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225996/
https://www.ncbi.nlm.nih.gov/pubmed/34179146
http://dx.doi.org/10.3389/fcvm.2021.687783