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TRPC1/5-Ca(V)3 Complex Mediates Leptin-Induced Excitability in Hypothalamic Neurons

Leptin regulates hypothalamic POMC(+) (pro-opiomelanocortin) neurons by inducing TRPC (Transient Receptor Potential Cation) channel-mediate membrane depolarization. The role of TRPC channels in POMC neuron excitability is clearly established; however, it remains unknown whether their activity alone...

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Detalles Bibliográficos
Autores principales: Perissinotti, Paula P., Martínez-Hernández, Elizabeth, Piedras-Rentería, Erika S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226082/
https://www.ncbi.nlm.nih.gov/pubmed/34177455
http://dx.doi.org/10.3389/fnins.2021.679078